9:00 – 9:45 Professor Cristin Print (University of Auckland)
Cancer Bioinformatics - How Hard Can It Be?
9:45 – 10:00 Dr Anna Trigos (Peter MacCallum Cancer Centre)
Diverse somatic mutation profiles drive common patterns of transcriptional rewiring related to loss of multicellularity in 10,000 cancer patients
10:00 – 10:15 Emma Gail (Monash University)
Molecular interactions as a framework to understand how the histone methyltransferase PRC2 is dysregulated by cancer-associated mutations
10:15 – 10:30 Andrew Lonsdale (Murdoch Children’s Research Institute)
Toblerone: Detecting deletions in cancer genes using RNA-seq
11:00 – 11:30 Professor Mark Cowley (Children's Cancer Institute of Australia)
Precision cancer bioinformatics for adults and children with advanced cancers
11:30 – 11:45 Dr Adria Closa (Australian National University)
Identification of RNA splicing therapeutic targets in high-risk paediatric acute leukaemia
11:45 – 11:50 Soroor Hediyah-Zadeh (The Walter and Eliza Hall Institute)
Supervised deconvolution of population heterogeneities in single cell RNA-seq via similarity-based embeddings
11:50 – 12:05 Dr Yi-Chih Chan (Peter MacCallum Cancer Centre)
Identification of epigenetic complexes driving haematopoiesis
12:05 – 12:10 Richard Lupat (Peter MacCallum Cancer Centre)
Unsupervised Feature Extraction from Breast Cancer Multi-Omics Data with Deep Learning Techniques
12:10 – 12:25 Dr Jacek Marzec (The University of Melbourne)
The role of RNA sequencing in providing comprehensive molecular characterisation of patient’s cancer
12:25 – 12:30 Holly Whitfield (The Walter and Eliza Hall Institute)
Post-Transcriptional Regulatory Networks within Breast Cancer Progression
Posters will be displayed in Lecture Theatres A & C, adjacent to main lecture theatre.
1:45 – 2:15 Professor Vanessa Hayes (Garvan Institute of Medical Research)
Missed messages in prostate tumour genomes
2:15 – 2:30 Dr Marek Cmero (Murdoch Children’s Research Institute)
MINTIE: identifying cryptic variants in cancer transcriptomes using RNA-seq data
2:30 – 2:45 Jared Mamrot (GMdX group)
Predicting patient response to immunotherapy using Innate Immune Fitness profiles
2:45 – 3:00 Chelsea Mayoh (Children’s Cancer Institute)
Whole Transcriptome Sequencing Improves Actionability in Children with High-Risk Cancer
3:30-3:45 Dr Daniel Cameron (The Walter and Eliza Hall Institute)
GRIDSS2: sensitive and specific somatic structural variant detection
3:45-3:50 Feng Yan (Monash University)
A 9-gene score for predicting B-ALL overall and relapse risk
3:50 – 4:05 Sebastian Hollizeck (Peter MacCallum Cancer Centre)
Opportunities and challenges of analysing multi-regional tumour biopsies to characterise heterogeneity in cancer
4:05-4:10 Hannah Huckstep (The Walter and Eliza Hall Institute)
Signalling networks in the Analysis of Proteomic Data
4:10-4:25 Serish Kanwal (The University of Melbourne)
Detecting and validating fusion genes from whole transcriptome sequencing data - challenges and insights
4:25-4:30 Dr Simon Keam (Peter MacCallum Cancer Centre)
Predicting radiation-induced immune trafficking and activation in localised prostate cancer.
4:30 – 5:00 Panel Discussion
Next challenges in cancer bioinformatics.
Venue: Castle Hotel - 56 Courtney St, North Melbourne